The reference site for Nortriptyline

Nortriptyline is a second-generation tricyclic antidepressant (TCA) marketed as the hydrochloride salt under the trade names Sensoval, Aventyl, Pamelor, Norpress, Allegron, Noritren and Nortrilen.

WHAT IS Nortriptyline?

Nortriptyline is a second generation tricyclic antidepressant, and it works by affecting chemicals in the brain that may become unbalanced and cause depression.

This medecine is used to relieve symptoms of depression such as feelings of sadness, worthlessness, guilt, loss of interest in daily activities, changes in appetite, tiredness, sleeping too much, insomnia, and even thoughts of death or suicide.

 

Brand Name(s): Aventyl; Pamelor
CAS nº: 894-71-3
(nor trip’ ti leen)

 

Product Info

The sections below will provide you with more specific information and guidelines related to nortriptyline and its correct use. Please read them carefully.

FDA Information

Nortriptyline was approved as an antidepressant by the FDA in 1964.

On October 15th 2004, the FDA directed manufacturers of all antidepressants to include a Black Box warning, expanded warning statements, and clinical trial results detailing the increased risk of suicidality in children and adolescents. A Patient Medication Guide (MedGuide) will also accompany all prescriptions for antidepressants.

Additionally, the FDA is currently assessing the risk of suicidality in adults taking antidepressants and a final report is expected by mid-to-late 2006.

Why is this medication prescribed?

Nortriptyline is a second generation tricyclic antidepressant. It affects chemicals in the brain that may become unbalanced and cause depression.

This medecine is used to relieve symptoms of depression such as feelings of sadness, worthlessness, or guilt; loss of interest in daily activities; changes in appetite; tiredness; sleeping too much; insomnia; and thoughts of death or suicide.

Other uses for this medicine

Nortriptyline is also used occasionally to treat panic disorders, chronic pain, premenstrual depression, and some skin conditions. It may also be used as an aid to quitting smoking.

However, it is important that you talk to your doctor about the possible risks of using this drug for your particular condition.

Dosage and using this medicine

Nortriptyline comes as a capsule and an oral liquid to be taken by mouth.

Take nortriptyline exactly as directed by your doctor. If you do not understand these directions, ask your pharmacist, nurse, or doctor to explain them to you.

Take each dose with a full glass (8 oz) of water.

Nortriptyline may be taken several times a day or in one daily dose (usually at bedtime). Follow your doctor’s instructions.

It may be 4 weeks or more before you start to feel better, but do not stop taking nortriptyline without first talking to your doctor.

What special precautions should I follow?

BEFORE TAKING NORTRIPTYLINE:

Tell your doctor if you have liver disease, kidney disease, asthma, thyroid disease, diabetes, stomach or intestinal problems, high blood pressure or heart disease, had a heart attack in the last 6 weeks, an enlarged prostate or difficulty urinating, or glaucoma. You may not be able to take nortriptyline, or you may require a dosage adjustment or special monitoring, if you have any of the conditions listed above.

Do not take nortriptyline if you have taken a monoamine oxidase inhibitor such as isocarboxazid (Marplan®), phenelzine (Nardil®), or tranylcypromine (Parnate®) within the last 14 days.

While you are taking nortriptyline you may need to be monitored for worsening symptoms of depression and/or suicidal thoughts at the start of therapy or when doses are changed. This concern about the increased risk of suicidal thoughts or behaviors may be greater if you are 18 years of age or younger and are taking nortriptyline. In patients younger than 18 years, the period of risk may extend beyond start of therapy or when doses are changed.

Your doctor may want you to monitor the following symptoms: anxiety, panic attacks, difficulty sleeping, irritability, hostility, impulsivity, severe restlessness, and mania (mental and/ or physical hyperactivity). These symptoms may be associated with the development of worsening symptoms of depression and/or suicidal thoughts or actions. Contact your healthcare provider if you develop any new or worsening mental health symptoms during treatment with nortriptyline. Do not stop taking nortriptyline.

It is not known whether nortriptyline will harm an unborn baby. Do not take nortriptyline without first talking to your doctor if you are pregnant or could become pregnant during treatment.

Furthermore, the effects of nortriptyline on a nursing baby are unknown. Do not take nortriptyline without first talking to your doctor if you are breast-feeding a baby.

Use cautiously when driving, operating machinery, or performing other hazardous activities. Nortriptyline may cause drowsiness or dizziness. If you experience drowsiness or dizziness, please avoid these activities completely.

Dizziness is likely to occur when you rise from a sitting or lying position. Rise slowly to prevent dizziness and a possible fall.

Additionally, consume alcohol in moderation. Alcohol may increase drowsiness and dizziness while you are taking nortriptyline.

What should I do if I forget a dose?

Take the missed dose as soon as you remember. If it is almost time for the next regularly scheduled dose, then skip the missed dose and take the next one as directed.

NEVER take a double dose of this medication unless otherwise directed by your doctor.

What side effects can this medication cause?

Side effects from using nortriptyline may include:

dizziness
drowsiness
dryness of mouth
headache
increased appetite (may include craving for sweets)
nausea
tiredness
weakness (mild)
unpleasant taste
weight gain

Tell your doctor if any of these symptoms are severe or do not go away:

constipation
mild tremor
sweating
mild agitation, weakness, or headache
ringing in the ears
nausea
loss of weight or appetite

If you experience any of the following symptoms, call your doctor immediately:

an allergic reaction (difficulty breathing; closing of the throat; swelling of the lips, face, or tongue; or hives)
seizures
a fast or irregular heartbeat
heart attack
high blood pressure (blurred vision, severe headache)
difficulty urinating
fever with increased sweating, muscle stiffness, or severe muscle weakness

Side effects other than those listed here may also occur. Talk to your doctor about any side effect that seems unusual or that is especially bothersome.

What storage conditions are needed for this medicine?

Keep this medication in the container it came in, tightly closed, and out of reach of children. Store it at room temperature and away from excess heat and moisture (not in the bathroom).

Throw away any medication that is outdated or no longer needed and, if necessary, consult your pharmacist about the proper disposal of your medication.

In case of an emergency/overdose

In case of an overdose, call your local poison control center at 1-800-222-1222. If the victim has collapsed or is not breathing, call local emergency services at 911.

Symptoms of overdose may include:

seizures
confusion
drowsiness
agitation
hallucinations
low blood pressure (dizziness, fatigue, fainting)

Product Images

PICTURES OF NORTRIPTYLINE PILLS

Below you will find images and specific information on the principal types of nortriptyline that exist, including their respective brand name(s), strength, inscription codes and manufacturers.

The information below includes general information and guidelines for patients taking this medication and should never be used to substitute professional medical advice that can be provided by a qualified physician or family doctor.

Name: NORTRIPTYLINE
Strength(s): 10 MG
Imprint: MYLAN 1410
Manufacturer: MYLAN

Name: NORTRIPTYLINE
Strength(s): 10 MG
Imprint: 10 MG 93 810
Manufacturer: TEVA USA

Name: PAMELOR®
Strength(s): 10 MG
Imprint: PAMELOR SANDOZ
Manufacturer: MALLINKRT PHARM.

Name: NORTRIPTYLINE
Strength(s): 10 MG
Imprint: NORTRIPTYLINE DAN 10 mg
Manufacturer: WATSON LABS.

Name: NORTRIPTYLINE
Strength(s): 25 MG
Imprint: GG 566
Manufacturer: GENEVA

Name: NORTRIPTYLINE
Strength(s): 25 MG
Imprint: MYLAN 2352
Manufacturer: MYLAN

Name: NORTRIPTYLINE
Strength(s): 25 MG
Imprint: 25 mg 93 811
Manufacturer: TEVA USA

Name: NORTRIPTYLINE
Strength(s): 25 MG
Imprint: NORTRIPTYLINE DAN 25 mg
Manufacturer: WATSON LABS.

Name: NORTRIPTYLINE
Strength(s): 50 MG
Imprint: MYLAN 3250
Manufacturer: MYLAN

Name: NORTRIPTYLINE
Strength(s): 50 MG
Imprint: 50 mg 93 812
Manufacturer: TEVA USA

Name: NORTRIPTYLINE
Strength(s): 50 MG
Imprint: NORTRIPTYLINE DAN 50 mg
Manufacturer: WATSON LABS.

Name: NORTRIPTYLINE
Strength(s): 75 MG
Imprint: MYLAN 4175
Manufacturer: MYLAN

Name: NORTRIPTYLINE
Strength(s): 75 MG
Imprint: 75 mg 93 813
Manufacturer: TEVA USA

Name: NORTRIPTYLINE
Strength(s): 75 MG
Imprint: NORTRIPTYLINE DAN 75 mg
Manufacturer: WATSON LABS.

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